分类： 医学、药学 >> 预防医学与公共卫生学 提交时间： 2023-03-29
William J. Liu
Peipei Liu
Wenwen Lei
Zhiyuan Jia
Xiaozhou He
Weifeng Shi
Yun Tan
Shumei Zou
Gary Wong
Ji Wang
Feng Wang
Gang Wang
Kun Qin
Rongbao Gao
Jie Zhang
Min Li
Wenling Xiao
Yuanyuan Guo
Ziqian Xu
Yingze Zhao
摘要： Emerging in December 2019, coronavirus disease 2019 (COVID-19) eventually became a pandemic and posed a tremendous threat to global public health. However, the origins of SARS-CoV-2, the causative agent of COVID-19, remain to be determined. It has been reported that a certain number of the early case clusters had a contact history with the Huanan Seafood Market. Therefore, surveillance of SARS-CoV-2 within the market is of vital importance. Herein, we presented the SARS-CoV-2 detection results of 1380 samples collected from the environment since 1st Jan and animals since 18th Jan within the market in early 2020. By SARS-CoV-2-specific RT-qPCR, 73 environmental samples tested positive for SARS-CoV-2 and three live viruses were successfully isolated. The viruses from the market shared nucleotide identity of 99.99% to 100% with the human isolate HCoV-19/Wuhan/IVDC-HB-01/2019. The A lineage (8782T and 28144C), as the likely ancestral SARS-CoV-2 lineage, was found in an environmental sample. No virus was detected in the animal swabs covering 18 species of animals in the market. The RNA-seq analysis of SARS-CoV-2 positive/negative environmental samples showed the abundance of different vertebrata genera. In summary, this study provided convincing evidence of the prevalence of SARS-CoV-2 in the Huanan Seafood Market during the early stage of COVID-19 outbreak.
分类： 光学 >> 量子光学 提交时间： 2023-02-19
摘要： Photonic bandgap design is one of the most basic ways to effectively control the interaction between light and matter. However, the traditional photonic bandgap is always dispersive (blueshift with the increase of the incident angle), which is disadvantageous to the construction of wide-angle optical devices. Hypercrystal, that the photonic crystal with layered hyperbolic metamaterials (HMMs), can strongly modify the bandgap properties based on the anomalous wavevector dispersion of the HMM. Here, based on phase variation compensation between HMM and isotropic dielectric layers, we propose for the first time to design nonreciprocal and flexible photonic bandgaps using magneto-optical HMMs in one-dimensional photonic crystals. Especially for the forward and backward incident light, the blueshift and dispersionless of the forward and backward cavity modes are designed respectively to realize the interesting omnidirectional nonreciprocal absorber. Our results show high (low) absorption about 0.99 (0.25) in an angle range of 20-75 degrees for the forward (backward) incident light at the wavelength of 367 nm. The nonreciprocal omnidirectional cavity mode not only facilitates the design of perfect unidirectional optical absorbers working in a wide-angle range, but also possesses significant applications for all-angle reflectors and filters.
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